gap mapping
Pick a gap from the Gap Map, research it, and talk about it! What does the problem entail? Why do we care about it? How do we solve it?
(Essentially a hackathon, but for research)
Example:
Let's say I'm interested in why we have no good predictors for unstable proteins. Questions I'd want to answer:
What makes AlphaFold so good at predicting static vs. dynamic structure? Are these problems inherent to self-play?
What do we know about the functions intrinsically disordered proteins play, and why do we care about them?
Why is NMR mapping and allosteric regulation prediction related to this problem? Are they essential bottlenecks? Could we get around them?
Convergent Research has made one of the best high-leverage problem lists in history, and we would be remiss to not pay attention to it.
Choose one to dive into and join us on Saturday!