Tapering Zoloft (sertraline)
About the Event
Join us for the next session in Outro’s Tapering Series, featuring Dr. Bryan Shapiro, Medical Advisor at Outro Health, for a focused discussion on Zoloft (sertraline)—one of the most widely prescribed SSRIs in the U.S. You will also have the opportunity to ask Dr. Shapiro questions during the Discussion Section towards end of the webinar!
While Zoloft is often seen as a more "tolerable" antidepressant, many patients still encounter significant challenges when discontinuing, particularly after long-term use. Dr. Shapiro will explore the unique withdrawal profile of sertraline, the neurobiological factors at play, and how Outro’s hyperbolic tapering method is helping patients come off medication more safely.
Can’t make it live? Register anyway and we’ll send you the recording.
🧠 What You’ll Learn
Why Zoloft discontinuation can still be difficult, despite its favorable reputation
What the latest research says about withdrawal symptoms and duration
How serotonin transporter dynamics impact tapering outcomes
Why hyperbolic tapering is more effective than linear dose reductions
How Outro’s virtual care model supports safe, structured tapering for Zoloft and other SSRIs
🎙️ Presenters
Dr. Bryan Shapiro
Dr. Shapiro is the Medical Advisor of Outro Health and a board-certified psychiatrist in California. He serves as a consultation-liaison psychiatrist and psychopharmacology educator at UC Irvine Medical Center and leads training for the UC Irvine/UC Davis Train New Trainers (TNT) program. Dr. Shapiro was involved in the early conceptualization of hyperbolic tapering and recently authored a paper on Cymbalta withdrawal. His unique blend of lived experience and academic leadership makes him a powerful speaker to safe antidepressant tapering.
Emma Frati
Emma leads Growth & Partnerships at Outro Health and with lived experience of psychiatric polypharmacy during her time at Columbia University. She holds a degree in Behavioral Neuroscience and has worked across psychedelic and wearables research, sleep science, and harm reduction advocacy.
About Outro
Outro is a virtual care platform providing safe, evidence-based antidepressant tapering. Using hyperbolic tapering—a neuroscience-informed approach—Outro helps patients reduce or discontinue medications with medical oversight and personalized support. Learn more at www.outro.com.