​The first North Carolina NUT Carcinoma Symposium will be a gathering of researchers working on any facet NUT carcinoma or the broader family of cancers driven by NUTM1 fusion proteins. Every flavor NUTM1-related research is welcome including mechanistic biology, preclinical models, case studies and therapeutic experiences, and novel therapeutic strategies.

The symposium will meet March 6th (9:30am - 4:30pm) and March 7th (9:30am - 1pm) in Room 340 in McLean Hall of the Rizzo Center (150 DuBose Home Lane, Chapel Hill, NC).

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Schedule

​Thursday March 6th

9:30 AM - Alex Rubinsteyn - Opening Remarks
9:35 AM - Jared Weiss - Overview of the clinical landscape for NUT carcinoma
10:00 AM - Kyle Eagen - BRD4-NUT Reprograms Chromatin 3D Structure
10:45 AM - Brandon Price - Genetic and Clinical Landscape of NUTM1 Structural Variants at Tempus
11:30 AM - Coffee Break
11:45 AM - Taylor Durall - Genetic screens and in vivo models of NUT carcinoma
12:30 PM - Lunch
1:30 PM - Bin Gu - Brd4::Nutm1 initiates NUT carcinoma in vivo
2:15 PM - Taylor Nguyen - The BRD4-NUT oncogenic fusion protein attenuates DDR signaling and sensitizes NUT carcinoma to radiotherapy
3:00 PM - Coffee Break
3:15 PM - Sara Peterson - Landscape of cancer/testis antigen expression in NUT carcinoma
4:00 PM - Alex Rubinsteyn - First Day Wrap-Up

Friday March 7th

9:30 AM - Alex Rubinsteyn - Design of a semi-personalized therapeutic vaccine targeting CTAs in NUT carcinoma
10:15 AM - Jochen Lorch - New investigator sponsored studies for patients with NUT carcinoma at Northwestern University
10:45 AM - Coffee Break
11:00 AM - Kristina Whately - Silent but Lethal: RNAi as a Weapon Against NUT Carcinoma
11:45 AM - Jeffrey Jensen - The Rise of HLA Restricted, T-Cell Receptor Therapeutics in Medical Oncology: Implications for NUT Carcinoma
12:30 PM - Panel
1:00 PM - Lunch