Exploring biotech origination: A fireside chat with Flagship Pioneering Partner, Jacob Rubens

​Join Nucleate UK and Flagship Pioneering for a fireside chat with Jacob Rubens.

​We are delighted to hear from Jake as he shares insights into his journey from fellow to partner at Flagship Pioneering, offering his perspective on Flagship’s unique venture origination model. Also join us to meet the Flagship Pioneering team and hear more about the opportunity to join their next cohort of Flagship Fellows in Summer 2025 🚀

​Jacob (Jake) is an Origination Partner at Flagship Pioneering. He is a scientist entrepreneur and leads a team that founds, builds, and grows companies based on new biotechnology.

​At Flagship, Jake co-founded Quotient Therapeutics, Sana Biotechnology and Tessera Therapeutics, and launched Kaleido Biosciences. Today, Jake is the CEO of Quotient, Flagship’s first company to be co-located in Cambridge, UK and Cambridge, MA. Jake began his Flagship career as a Fellow in 2015 and has since become the first former Fellow to be named a Pioneering Business Unit (PBU) lead, one of the most senior positions at the company.

​Before joining Flagship, Jake received his PhD in microbiology from MIT, working in the Synthetic Biology Center with Professor Tim Lu with the support of a National Science Foundation Graduate Research Fellowship.

​Jake’s work has resulted in multiple pending patents and publications, including articles in Nature and Nature Communications. Jake was honored in 2017 in Forbes' 30 under 30 list in science, in 2021 in Endpoints’ 20(+1) Under 40 list of the next generation of biotech leaders, and in 2021 in Business Insiders’ list of 12 young serial entrepreneurs building the next generation of biotech startups.​

​Event Schedule

• ​6:00–6:30 pm – Arrival and networking

• ​6:30–6:45 pm – Introductions to Nucleate and the Flagship fellowship

• ​6:45–7:30 pm – Fireside chat with Jake Rubens, discussing his experience at Flagship, their unique model and the Fellowship role

• ​7:30–9:00 pm – Drinks and networking with former Fellows